Mass Effect 3

- For your first time through, play Soldier, Sentinel, or Infiltrator. Biotic powers are actually quite worthwhile now, but so is shooting things.

- Don't feel bound to the types of weapons you were using in the first two games. Wanna play an Infiltrator with a shotgun and an SMG? Go for it. How about a Sentinel with an assault rifle and a shotgun-pistol? Sure! Use the shooting range on the Citadel to get the hang of your new gear.

- Some guns can only be found on missions and are missable, so look around!

- Complete armor sets (the ones that cost 50000) have kinda crappy stats. Don't bother, unless you like the look.

- Do every sidequest you get before doing the next "Priority:" mission. The exception is Eden Prime, which is the mission for the DLC character.

- When given the choice between betraying your old friend, and getting the support of the other race, stick with your buddy. You can get the other guys' support anyways later on. If I had to tell you that for you to make that decision, you're an asshole.

- It IS possible to make the warring races near the middle of the game get along, but if you didn't do the loyalty missions for the two squadmates involved in ME2, or got one of them exiled, you won't be able to do it. If you don't manage it, know that at least one of them will die.

- They make it fairly clear when you're about to go on the point of no return mission, but for the sake of it, it's a place called Cronos Station.