Fable: The Lost Chapters

Max out Physical Shield and Slow Time as soon as possible. Also, the Heal Life spell also heals friendly/neutral NPCs around you, making it useful for escort missions early on in the game, so go for at least one level of that as well. Combine all that with the fact that you are invincible while rolling, and you're guaranteed to never die, or even take much, if any, damage.

A trick to get a lot of strength XP relatively early in the game (which is important for defense as well as offense): max out your attractiveness so that you can get married and then when you are alone with your wife in your house, start attacking her. Position yourself so that she's trapped up against the wall or a piece of furniture or something so she can't get away and just repeatedly hit the attack button. This will drive your combat multiplier way up. You can do this forever without killing her but once you stop she will divorce you so you have to do it all at once rather than dole out a bunch of little beatings. Sometimes a guard will catch you but it's unusual and you can just teleport out of there before you have to pay a fine.