- You can always backtrack if you realise you've missed a collectible, though it may take a long time. Note that there is a point of no return, but the game makes it extremely obvious, and there are no collectibles after that point.
- There are several missable collectibles, five videos specifically, so if 100% completion is important than it's worth looking them up.
- Most weapons (aside from your starting sidearm and a weapon received during a specific setpiece) are locked behind puzzles, but keep an extra eye out for Alan's shotgun, it can be found before you enter the second overlap area.
- Dodging is key to combat, you get i-frames and dodging the final hit in an enemies combo will stun it.
- The game has adaptive loot drops, so hording items won't get you ahead. Use whatever you have available to you to survive.
- Stealth is very viable. Physical Taken are harder to avoid, but you can pass right next to Shadows as long as it's dark and you aren't running.
- Most Plot important rooms seem to reset enemy AI, so running past enemies to enter one is a viable strategy.
- Use your flashlight burst liberally. It will reveal a weakpoint on some enemies, remove the darkness shield on others, and cause the rest to stumble.
- Flares are a flashlight burst that last much longer and can be thrown. They're also a "personal space" emergency option that will cause enemies to back off and give you some space.
- Watch for painted rocks and hung knit art while exploring, these will lead you to the lunchbox collectibles.