- If you're using a Maiming weapon, you can massacre regular zombies (walkers/runners) by aiming for the legs.
- If your weapon has an elemental mod some zombie subtypes will be completely immune to it. Make sure to have a backup. A purely physical one is good to have on-hand for firefighters.
- Top up your Fuse supply every time you visit a vendor. Spend one when you're feeling like you need a new weapon.
- Lockboxes usually can't be opened when you first find them. They're for when you return to areas.
- Don't underestimate the humble Meat Bait and Chem Bomb. They might not do any damage, but that doesn't mean you can't massacre zombies with them.