- The fanmade "Hong Kong Bugfix Compilation" is very recommended to fix a number of issues with various abilities and bonuses.
- You get any number of "urgent" missions that you can put off forever. The only one that has an actual time limit is Strangler Bao's request.
- The first few missions feature fairly worthless paydata, but latter runs will have data sales that will give you about 1/3 of the total payment for that run.
- Take Gobbet along to the feng-shui mission.
- If you want to get the best ending, make sure to talk to at least Crafty and Is0bel regularly. There's also a phrase you can select to end an argument at one point some ways into the game, keep that phrase in mind for later.
- Useful etiquettes include Shadowrunner, Academic (mostly for bits of info rather than tangible benefit) and Gang/Corporate.
- The Auto-Loader arm is a piece of cyberware that can be purchased once you've done three missions or so. It automatically reloads pretty much every gun / grenade launcher / minigun you can find. Immensely useful for any build that relies on ranged weapons.
- The Shiawase Loader arm automatically throws back any grenades that land near you. Useful, but: you need strength to throw grenades accurately, arm cyberware slots have a lot of other neat choices, and Duncan has this as an upgrade option.
- Companion specialization notes:
- Duncan: the tier 6 Magnet arm (catch and throw back grenades) is straight up silly overpowered. Cluster in groups, bait grenades, profit.
- Is0bel: you can buy her tier 4 Espionage upgrade (+40% Matrix move speed) at Maximum Law's for 500 nuyen and loan it to her if you're so inclined. The 6 extra Fire damage DoT on the grenade launcher (which is great, by the way) is worth either putting up with slower Matrix movement or a nominal investment.
- Gobbet: the tier 5 Plague Wall spell is actually a reusable inventory item with a cooldown, which lets you fill that other slot with any other spell you desire without pushing anything off her default loadout. There's a case to be made for the free Devil Rat token if you've invested heavily in the Spirituality track, but Plague Wall is special.
- Gaichu: this may be obvious to you, but it wasn't to me; his tier 3 Shuriken Toss is a Strength attack, which means that it deals the listed 12 damage plus Gaichu's Strength and it pops cover.
- Racter: Spec his drone to be a sniper or a melee beast. Mixing and matching doesn't work that well. If you go melee: the drone isn't terrible accurate, so be prepared to supplement this with abilities.