This wiki is a compilation of the advice offered at the Something Awful thread.
To see tips, visit the Game List, or use the Search Box.
If you can't find a game on the list, then you can search through the thread by entering the following in Google:
site:forums.somethingawful.com intitle:"What Should I Know" "Game Name Here"
If you want to contribute, read the Help page.
WARNING: Some of the tips may contain spoilers!