Dead Space 2

- You want a long-range gun and a close range crowd control weapon, as well as your plasma cutter and a "special event" weapon, probably either the mine launcher or contact beam. The javelin gun can work well as a long range one. For close range, consider the force gun or line gun. Even the flamethrower is a little better this time around.

- Nodes put into the plasma cutter are never wasted. Seriously, that thing is absolutely awesome. The circular saw is also great to incapacitate quickly most of the enemies, just be sure to finish them off or else you'll get crowds of legless monsters after you in the latest parts of the game.